(±)-2-(2-Fluoro-[1,1′-biphenyl]-4-yl)-N-(1-phenylpropan-2-yl)propanamide
نویسندگان
چکیده
2-(2-fluoro-[1,1′-biphenyl]-4-yl)-N-(1-phenylpropan-2-yl)propanamide was synthesized by a reaction between amphetamine and flurbiprofen in high yields. The newly obtained hybrid molecule fully analyzed characterized via 1H, 13C, UV, IR, HPLC, mass spectral data.
منابع مشابه
2-(Biphenyl-4-yl)propan-2-ol
The title compound, C(15)H(16)O, crystallizes with two independent mol-ecules in the asymmetric unit. Due to the space-group symmetry, this results in the formation of a tetra-mer where the four mol-ecules are connected by O-H⋯O hydrogen bonds. The mol-ecules pack parallel to the c axis. Both mol-ecules in the asymmetric unit are nonplanar and the dihedral angles between connected aromatic ring...
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The asymmetric unit of the title compound, C(19)H(15)FN(2)O(2), contains two mol-ecules, A and B, in which the dihedral angles between the ring systems are 46.4 (2) and 17.24 (14)°, respectively. In the crystal, mol-ecules are linked into [010] chains of alternating A and B species by N-H⋯O hydrogen bonds.
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A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...
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ژورنال
عنوان ژورنال: Molbank
سال: 2022
ISSN: ['1422-8599']
DOI: https://doi.org/10.3390/m1319